To amend the Philadelphia Zoning Maps by changing the zoning designations of certain areas of land located within an area bounded by South Street, the Schuylkill River, 34th Street, University Avenue, Civic Center Boulevard, and Health Sciences Drive; and to approve amendments to the University of Pennsylvania Master Plan in the area bounded by South Street, the Schuylkill River, 34th Street, University Avenue, Civic Center Boulevard, and Health Sciences Drive, related to the proposed Ott Center building at 2910 South Street and other previously approved minor amendments.